It was seen that the number of Pseudomonas aeruginosa isolates were greater than the number of Acinetobacter in all the four months. For result analysis and computation, antimicrobial profile of both Acinetobacter species and Pseudomonas aeruginosa obtained from multiple swabs were added together. It was also observed that most of the P. aeruginosa and Acinetobacter isolates were highly resistant to antibiotics. The total number of P. aeruginosa isolates were 152/271.Most of the P. aeruginosa isolates were highly resistant to antibiotics- ceftazidime (88.8%), amikacin (95.3%), ciproflox (96%), netilmicin (92.6%), cefoperazone + sulbactam (83.5%) meropenam (74.3%), piperacillin + tazobactam (61.8%). 60% of these isolates were sensitive to imipenam. The total number of Acinetobacter isolates were 119/271. Acinetobacter isolates collected were highly resistant to ceftazidime (100%), amikacin (99%), ciproflox (98.3%), cefoperazone + sulbactam (56. 3%), meropenam (94.9%), piperacillin + tazobactam (86.5%) and imipenam (61.3%). 64.4% of these strains were sensitive to netilmicin.