Author(s): Mayani Chaodhary

Abstract:
There are about 300 hypotheses that attempt to explain the ageing process. Many of them are based on the analysis of cumulative changes over time. The free radical hypothesis of ageing, proposed initially by Harman and based on the molecular nature and ubiquitous existence of free radicals, is the most popular and thoroughly tested of all the hypotheses. The goal of this study is to summaries numerous studies on the subject. This review will summaries different research on the function of free radicals in DNA damage, oxidative stress, antioxidants, the existence of auto antibodies, and their influence on the ageing process.